1. No global outbreaks, but localized and targeted attacks
2. It’s all about money, so cybercrime will not go away
3. Windows 7 will have an impact since it is less secure than Vista in the default configuration
4. Drive-by infections are the norm—one Web visit is enough to get infected
5. New attack vectors will arise for virtualized/cloud environments
6. Bots cannot be stopped anymore, and will be around forever
7. Company/Social networks will continue to be shaken by data breaches
8. Web threats will continue to plague Internet users

Source.